high dose, repeated administration) may cause persisting hallucinations and impairments in cognition & memory. Anecdotal reports suggest that chronic use (i.e. The toxicity of recreational use is not well-studied. It is generally considered to have low abuse potential due to its dysphoric effects. Most people who try diphenhydramine do not report positive effects and do not wish to repeat the experience. Notably, it is frequently reported to produce significant nausea and bodily discomfort ("body load"). Doses between these two points are uncomfortable and dysphoric. Lower doses tend to produce a stoning, body-high effect while higher doses produce a state of delirium in which the user sees and hears fully-formed, extremely convincing hallucinations. Subjective effects include sedation, anxiety, tactile hallucinations, memory suppression, thought disorganization, dysphoria, and external hallucinations. Today, it is typically used to treat allergies, but it may also be used for a number of conditions including itchiness, insomnia, motion sickness, nausea and the symptoms of Parkinson's disease. It was approved for over-the-counter use in the 1980s. In 1946, it became the first prescription antihistamine approved by the U.S. When exceeding approved doses, diphenhydramine produces powerful deliriant effects.ĭiphenhydramine was first synthesized in 1943. It is a first-generation H 1 antihistamine that is widely used as a generic, over-the-counter medication to treat allergies. It is not a recommendation and should be verified with other sources for accuracy.ĭiphenhydramine (also known as DPH, Dimedrol, Benadryl, and many others) is a deliriant substance of the ethanolamine class. See responsible use section.ĭISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only.
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. DPH, Benadryl, Nytol, Sominex, Unisom SleepMelts, ZzzQuilĢ-(diphenylmethoxy)-N,N-dimethylethanamine
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